Thirty-two (32) student groups operate in DUTH. Twenty (20) of them are undergraduate student groups for almost every School and seven (7) are postgraduate student groups. Furthermore, there are two (2) clubs of intern students in Komotini and Xanthi.
There are also three (3) Cultural Clubs:
the Youth Community in Komotini,
Gefira in Xanthi, and
the Academic Citizens Club, in Alexandtoupoli.